A Novel Three-Stage Framework for Association Analysis Between SNPs and Brain Regions

Motivation: At present, a number of correlation analysis methods between SNPs and ROIs have been devised to explore the pathogenic mechanism of Alzheimer's disease. However, some of the deficiencies inherent in these methods, including lack of statistical efficacy and biological meaning. This s...

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Bibliographic Details
Main Authors: Juan Zhou, Yangping Qiu, Shuo Chen, Liyue Liu, Huifa Liao, Hongli Chen, Shanguo Lv, Xiong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.572350/full