Novel ELISA method as exploratory tool to assess immunity induced by radiated attenuated sporozoites to decipher protective immunity

Abstract Background Whole parasite vaccines provide a unique opportunity for dissecting immune mechanisms and identify antigens that are targeted by immune responses which have the potential to mediate sterile protection against malaria infections. The radiation attenuated sporozoite (PfSPZ) vaccine...

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Bibliographic Details
Main Authors: Trey A. Knepper, Elizabeth H. Duncan, Tatyana Savransky, Elke S. Bergmann-Leitner
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-017-2129-9