Lipid-Lowering Effects of Ethyl 2-Phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in Rodents

Lipid-Lowering Effects of Ethyl 2-Phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in Rodents

A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole deri...

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Bibliographic Details
Main Authors: Bruce S. Burnham, John T. Gupton, Keith Krumpe, John R. Lukens, Robert B. Miller, Joshua D. Berkowitz, Bryan J. McCranor, Kam Suet Lam, Josephine Glersaye, Ulander Miott, Brett M. Taylor, Donna L. Wilson, Shahzad Rifat, Gerard A. Dalglish, Daniel C. Smith, Michael A. Evans, Anthony Argenti, Adam Getzel, Kathy O'Toole-Colin, Justin M. Holub
Format: Article
Language:English
Published: MDPI AG 2004-02-01
Series:Molecules
Subjects:
Pyrrole
hypolipidemia
cholesterol
triglyceride
Online Access:http://www.mdpi.com/1420-3049/9/3/134/

Internet

http://www.mdpi.com/1420-3049/9/3/134/

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