Functional Classification of <i>TP53</i> Mutations in Acute Myeloid Leukemia

Functional Classification of <i>TP53</i> Mutations in Acute Myeloid Leukemia

Mutations of the <i>TP53</i> gene occur in a subset of patients with acute myeloid leukemia (AML) and confer an exceedingly adverse prognosis. However, whether different types of <i>TP53</i> mutations exert a uniformly poor outcome has not been investigated yet. Here, we addr...

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Bibliographic Details
Main Authors: Sayantanee Dutta, Gudrun Pregartner, Frank G. Rücker, Ellen Heitzer, Armin Zebisch, Lars Bullinger, Andrea Berghold, Konstanze Döhner, Heinz Sill
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
acute myeloid leukemia
<i>tp53</i> mutations
functional classification
relative fitness core
prognosis
Online Access:https://www.mdpi.com/2072-6694/12/3/637

Internet

https://www.mdpi.com/2072-6694/12/3/637

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