ECT2 overexpression promotes the polarization of tumor-associated macrophages in hepatocellular carcinoma via the ECT2/PLK1/PTEN pathway

ECT2 overexpression promotes the polarization of tumor-associated macrophages in hepatocellular carcinoma via the ECT2/PLK1/PTEN pathway

Abstract Hepatocellular carcinoma (HCC) is a common high-mortality cancer, mainly due to diagnostic difficulties during its early clinical stages. In this study, we aimed to identify genes that are important for HCC diagnosis and treatment, and we investigated the underlying mechanism of prognostic...

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Bibliographic Details
Main Authors: Dafeng Xu, Yu Wang, Jincai Wu, Zhensheng Zhang, Jiacheng Chen, Mingwei Xie, Rong Tang, Cheng Chen, Liang Chen, Shixun Lin, Xiangxiang Luo, Jinfang Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03450-z

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https://doi.org/10.1038/s41419-021-03450-z

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