Reaction of ethyl acetoacetate and 2′-hydroxychalcones: Efficient route to 9-aryl-6H-benzo[c]chromen-6-ones

The reaction of ethyl acetoacetate and 2′-hydroxychalcones under atmospheric air to furnish a series of functionalized 6H-benzo[c]chromen-6-ones in moderate yields is reported. The reaction proceeds through trans-esterification, intra-molecular Michael addition, Robinson annulation and oxidative aro...

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Bibliographic Details
Main Authors: I. B. Masesane, O. Mazimba
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2014-05-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:http://www.ajol.info/index.php/bcse/article/view/103690