Effect of oral genistein administration in early and late phases of allergic encephalomyelitis

Effect of oral genistein administration in early and late phases of allergic encephalomyelitis

Objective(s):Experimental allergic encephalomyelitis (EAE) is an autoimmune disease validated as animal model of multiple sclerosis (MS). Administration of genistein, a phytoestrogenic component of soy, to mice at the onset of EAE is known to attenuate the clinical signs of the disease. The potentia...

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Bibliographic Details
Main Authors: Soodeh Razeghi Jahromi, Seyed Rafi Arrefhosseini, Amir Ghaemi, Akram Alizadeh, Fateme Sabetghadam, Mansoureh Togha
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-07-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Experimental allergic encephalomyelitis (EAE)
Genistein
Immunomodulation
Interferon-gamma
Multiple Sclerosis
Online Access:http://ijbms.mums.ac.ir/pdf_3030_285edbf09af7a76583e77b4bdf8b06ff.html

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http://ijbms.mums.ac.ir/pdf_3030_285edbf09af7a76583e77b4bdf8b06ff.html

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