Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains[S]

Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains[S]

Vascular damage caused by Shiga toxin (Stx)-producing Escherichia coli is largely mediated by Stxs, which in particular, injure microvascular endothelial cells in the kidneys and brain. The majority of Stxs preferentially bind to the glycosphingolipid (GSL) globotriaosylceramide (Gb3Cer) and, to a l...

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Bibliographic Details
Main Authors: Josefine Betz, Martina Bielaszewska, Andrea Thies, Hans-Ulrich Humpf, Klaus Dreisewerd, Helge Karch, Kwang S. Kim, Alexander W. Friedrich, Johannes Müthing
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Journal of Lipid Research
Subjects:
glycolipid
caveolae
DRM
Gb3Cer
Gb4Cer
caveolin-1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408971

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http://www.sciencedirect.com/science/article/pii/S0022227520408971

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