Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis.

Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis.

Integrating evidence from multiple domains is useful in prioritizing disease candidate genes for subsequent testing. We ranked all known human genes (n=3819) under linkage peaks in the Irish Study of High-Density Schizophrenia Families using three different evidence domains: 1) a meta-analysis of mi...

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Bibliographic Details
Main Authors: Zhongming Zhao, Bradley T Webb, Peilin Jia, T Bernard Bigdeli, Brion S Maher, Edwin van den Oord, Sarah E Bergen, Richard L Amdur, Francis A O'Neill, Dermot Walsh, Dawn L Thiselton, Xiangning Chen, Carlos N Pato, International Schizophrenia Consortium, Brien P Riley, Kenneth S Kendler, Ayman H Fanous
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726675?pdf=render

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http://europepmc.org/articles/PMC3726675?pdf=render

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