Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain

Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain

1,4-Dihydropyridines (DHPs) are the most important class of L-type calcium channel blockers that are employed for the treatment of cardiovascular diseases, particularly hypertension. Various modifications on this scaffold lead to the discovery of new DHPs blocking different types of calcium channels...

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Bibliographic Details
Main Authors: Giuseppina Ioele, Rita Muzzalupo, Miyase Gözde Gündüz, Michele De Luca, Elisabetta Mazzotta, Fedora Grande, Maria Antonietta Occhiuzzi, Antonio Garofalo, Gaetano Ragno
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
T-type calcium channel blockers
multivariate curve resolution
drug photostability
Pluronic<sup>®</sup> surfactants
α-tocopherol
Online Access:https://www.mdpi.com/1999-4923/13/4/527

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https://www.mdpi.com/1999-4923/13/4/527

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