Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

Single-cell RNA sequencing allows characterizing cell-to-cell heterogeneity at transcriptome scale. Here, the authors present an approach that enables microRNA and mRNA sequencing in the same single cell, providing insights into the origins of non-genetic cellular variability and mechanisms of miRNA...

Full description

Bibliographic Details
Main Authors: Nayi Wang, Ji Zheng, Zhuo Chen, Yang Liu, Burak Dura, Minsuk Kwak, Juliana Xavier-Ferrucio, Yi-Chien Lu, Miaomiao Zhang, Christine Roden, Jijun Cheng, Diane S. Krause, Ye Ding, Rong Fan, Jun Lu
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07981-6

Internet

https://doi.org/10.1038/s41467-018-07981-6

Similar Items