Dimethyl itaconate protects against lipopolysaccharide-induced endometritis by inhibition of TLR4/NF-κB and activation of Nrf2/HO-1 signaling pathway in mice

Dimethyl itaconate protects against lipopolysaccharide-induced endometritis by inhibition of TLR4/NF-κB and activation of Nrf2/HO-1 signaling pathway in mice

<em><strong>Objective(s):</strong></em> Endometritis is the inflammation of the uterine lining that is associated with infertility. It affects milk production and reproductive performance and leads to huge economic losses in dairy cows. Dimethyl itaconate (DI), a promising ch...

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Bibliographic Details
Main Authors: Mingyue Xu, Peng Jiang, Haowen Sun, Xin Yuan, Siyuan Gao, Jian Guo, Caijun Zhao, Xiaoyu Hu, Xueshibojie Liu, Yunhe Fu
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
dimethyl itaconate endometritis lps nf
κb nrf2 tlr4
Online Access:http://ijbms.mums.ac.ir/article_16170_7d23d74288e60f270a9a6fbb15ab0ea7.pdf

Internet

http://ijbms.mums.ac.ir/article_16170_7d23d74288e60f270a9a6fbb15ab0ea7.pdf

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