A resource of high-quality and versatile nanobodies for drug delivery

A resource of high-quality and versatile nanobodies for drug delivery

Summary: Therapeutic and diagnostic efficacies of small biomolecules and chemical compounds are hampered by suboptimal pharmacokinetics. Here, we developed a repertoire of robust and high-affinity antihuman serum albumin nanobodies (NbHSA) that can be readily fused to small biologics for half-life e...

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Bibliographic Details
Main Authors: Zhuolun Shen, Yufei Xiang, Sandra Vergara, Apeng Chen, Zhengyun Xiao, Ulises Santiago, Changzhong Jin, Zhe Sang, Jiadi Luo, Kong Chen, Dina Schneidman-Duhovny, Carlos Camacho, Guillermo Calero, Baoli Hu, Yi Shi
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Drug Delivery System
Biochemical Engineering
Biotechnology
Structural Biology
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009822

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http://www.sciencedirect.com/science/article/pii/S2589004221009822

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