Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms

Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms

Deep brain stimulation (DBS) is a symptomatic treatment of Parkinson’s disease (PD) that benefits only a minority of patients. Here, the authors show that activation of cortical somatostatin interneurons alleviates motor symptoms in a mouse model of PD and may constitute a less invasive alternative...

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Bibliographic Details
Main Authors: Sébastien Valverde, Marie Vandecasteele, Charlotte Piette, Willy Derousseaux, Giuseppe Gangarossa, Asier Aristieta Arbelaiz, Jonathan Touboul, Bertrand Degos, Laurent Venance
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16046-6

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https://doi.org/10.1038/s41467-020-16046-6

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