Design considerations for early-phase clinical trials of immune-oncology agents

Abstract Background With numerous and fast approvals of different agents including immune checkpoint inhibitors, monoclonal antibodies, or chimeric antigen receptor (CAR) T-cell therapy, immunotherapy is now an established form of cancer treatment. These agents have demonstrated impressive clinical...

Full description

Bibliographic Details
Main Authors: Nolan A. Wages, Cody Chiuzan, Katherine S. Panageas
Format: Article
Language:English
Published: BMJ Publishing Group 2018-08-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40425-018-0389-8