The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib

The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib

Background: Chorea-acanthocytosis (ChAc) is a rare hereditary neurodegenerative disease with deformed red blood cells (RBCs), so-called acanthocytes, as a typical marker of the disease. Erythrocyte sedimentation rate (ESR) was recently proposed as a diagnostic biomarker. To date, there is no treatme...

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Bibliographic Details
Main Authors: Antonia Rabe, Alexander Kihm, Alexis Darras, Kevin Peikert, Greta Simionato, Anil Kumar Dasanna, Hannes Glaß, Jürgen Geisel, Stephan Quint, Adrian Danek, Christian Wagner, Dmitry A. Fedosov, Andreas Hermann, Lars Kaestner
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomolecules
Subjects:
acanthocytes
dasatinib
erythrocyte sedimentation rate
3D shapes
microfluidics
phase diagram
Online Access:https://www.mdpi.com/2218-273X/11/5/727

Internet

https://www.mdpi.com/2218-273X/11/5/727

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