Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display.

BACKGROUND:Leptospirosis is the most common zoonotic disease worldwide. The diagnostic performance of a serological test for human leptospirosis is mainly influenced by the antigen used in the test assay. An ideal serological test should cover all serovars of pathogenic leptospires with high sensiti...

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Bibliographic Details
Main Authors: Siti Roszilawati Ramli, Gustavo M S G Moreira, Jonas Zantow, Marga G A Goris, Van Kinh Nguyen, Natalia Novoselova, Frank Pessler, Michael Hust
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007131