Ab-initio study of pyrrole ring deformation in the indole group of 5-HT interacting with water molecules

5-Hydroxytryptamine (5-HT; serotonin) regulates metabolism and various homeostatic mechanisms in the body, and is involved in depression. These complicated functions of 5-HT are supported by several 5-HT receptor and 5-HT transporter subtypes. The development of agonists/antagonists and activators/i...

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Bibliographic Details
Main Authors: Kei Odai, Tohru Sugimoto, Etsuro Ito
Format: Article
Language:English
Published: The Biophysical Society of Japan 2019-08-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.16.0_127