KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology

Abstract The voltage-dependent potassium channel Kv1.3 plays essential roles in the immune system, participating in leukocyte activation, proliferation and apoptosis. The regulatory subunit KCNE4 acts as an ancillary peptide of Kv1.3, modulates K+ currents and controls channel abundance at the cell...

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Bibliographic Details
Main Authors: Albert Vallejo-Gracia, Daniel Sastre, Magalí Colomer-Molera, Laura Solé, María Navarro-Pérez, Jesusa Capera, Sara R. Roig, Oriol Pedrós-Gámez, Irene Estadella, Orsolya Szilágyi, Gyorgy Panyi, Péter Hajdú, Antonio Felipe
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94015-9