MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERα) in regulation of the MUC1 gene expression

<p>Abstract</p> <p>Background</p> <p>The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors its transcription is dramatically upregulated. Of particular relevance to...

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Bibliographic Details
Main Authors: Wreschner Daniel H, Gorivodsky Marat, Aylon Yael, Barnea Itay, Zaretsky Joseph Z, Keydar Iafa
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/57