Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice

Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice

Social behaviour is regulated by activity of host-associated microbiota across multiple species. However, the molecular mechanisms mediating this relationship remain elusive. We therefore determined the dynamic, stimulus-dependent transcriptional regulation of germ-free (GF) and GF mice colonised po...

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Bibliographic Details
Main Authors: Roman M Stilling, Gerard M Moloney, Feargal J Ryan, Alan E Hoban, Thomaz FS Bastiaanssen, Fergus Shanahan, Gerard Clarke, Marcus J Claesson, Timothy G Dinan, John F Cryan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
Social behaviour
neurodevelopment
microbiome
amygdala
activity-dependent transcription
autism
Online Access:https://elifesciences.org/articles/33070

Internet

https://elifesciences.org/articles/33070

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