Characterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice

Characterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice

Brusatol (BR) is one of the main bioactive components derived from Brucea javanica, a medicinal herb historically used in the treatment of dysenteric disorders (also known as ulcerative colitis(UC)). Due to its poor aqueous solubility, a novel brusatol self-microemulsifying drug delivery system (BR-...

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Bibliographic Details
Main Authors: Jiangtao Zhou, Lihua Tan, Jianhui Xie, Zhengquan Lai, Yanfeng Huang, Chang Qu, Dandan Luo, Zhixiu Lin, Ping Huang, Ziren Su, Youliang Xie
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
brusatol
self-microemulsifying drug delivery system
in vitro and in vivo evaluation
anti-colitis activity
anti-inflammation
Online Access:http://dx.doi.org/10.1080/10717544.2017.1384521

Internet

http://dx.doi.org/10.1080/10717544.2017.1384521

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