Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats

CONTEXT: Methotrexate and other anticancer agents can induce intestinal mucositis, which is one of the most common limiting factor that prevent further dose escalation of the methotrexate. OBJECTIVES: To evaluate the gastric emptying and gastrointestinal transit of liquids in methotrexate-induced in...

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Bibliographic Details
Main Authors: Pedro M. G. Soares, Lorena O. Lopes, José Maurício S. C. Mota, José Nelson Belarmino-Filho, Ronaldo A. Ribeiro, Marcellus Henrique L. P. de Souza
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2011-03-01
Series:Arquivos de Gastroenterologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000100016&lng=en&tlng=en