Application of Comparative Genomic Hybridization, Spectral Karyotyping, and Microarray Analysis in the Identification of Subtype-Specific Patterns of Genomic Changes in Rhabdomyosarcoma

Application of Comparative Genomic Hybridization, Spectral Karyotyping, and Microarray Analysis in the Identification of Subtype-Specific Patterns of Genomic Changes in Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) in children occurs predominantly as two major histologically defined subtypes called embryonal RMS (RMS-E) and the prognostically less favorable alveolar RMS (RMS-A). Comparative genomic hybridization (CGH) was performed on 21 RMS and identified consistent gains affecting chr...

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Bibliographic Details
Main Authors: Ajay Pandita, Maria Zielenska, Paul Thomer, Jane Bayani, Roseline Godbout, Mark Greenberg, Jeremy A. Squire
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
rhabdomyosarcoma
CGH
SKY
microarray
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800463

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http://www.sciencedirect.com/science/article/pii/S1476558699800463

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