Signaling Pathways Regulating Redox Balance in Cancer Metabolism

The interplay between rewiring tumor metabolism and oncogenic driver mutations is only beginning to be appreciated. Metabolic deregulation has been described for decades as a bystander effect of genomic aberrations. However, for the biology of malignant cells, metabolic reprogramming is essential to...

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Bibliographic Details
Main Authors: Maria Chiara De Santis, Paolo Ettore Porporato, Miriam Martini, Andrea Morandi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00126/full