HIF-1α or HOTTIP/CTCF Promotes Head and Neck Squamous Cell Carcinoma Progression and Drug Resistance by Targeting HOXA9

Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequently diagnosed cancer worldwide. However, the clinical outcomes remain unsatisfactory. The aim of this study is to unravel the functional role and regulatory mechanism of HOXA9 in HNSCC. A cohort of 25 HNSCC tumor tissues and norm...

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Bibliographic Details
Main Authors: Qiang Sun, Shuai-Yuan Zhang, Jun-Fang Zhao, Xin-Guang Han, Hai-Bin Wang, Ming-Lei Sun
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300809