Hypocretin Levels in Sporadic and Familial Cases of Canine Narcolepsy

Hypocretin Levels in Sporadic and Familial Cases of Canine Narcolepsy

Familial and sporadic forms of narcolepsy exist in both humans and canines. Mutations in the hypocretin receptor 2 gene (Hcrtr 2) cause canine familial narcolepsy. In humans, mutations in hypocretin-related genes are rare, but cerebrospinal fluid (CSF) hypocretin-1 is undetectable in most sporadic c...

Full description

Bibliographic Details
Main Authors: Beth Ripley, Nobuhiro Fujiki, Mutsumi Okura, Emmanuel Mignot, Seiji Nishino
Format: Article
Language:English
Published: Elsevier 2001-06-01
Series:Neurobiology of Disease
Subjects:
hypocretin
orexin
narcolepsy
CSF
radioimmunoassay
immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996101903894

Internet

http://www.sciencedirect.com/science/article/pii/S0969996101903894

Similar Items