Temporal intra-individual variation of immunological biomarkers in type 1 diabetes patients: implications for future use in cross-sectional assessment.

Temporal intra-individual variation of immunological biomarkers in type 1 diabetes patients: implications for future use in cross-sectional assessment.

Multiple immune parameters such as frequencies of autoreactive CD4(+), CD8(+) T-cells and CD4(+)CD25(+)Foxp3(+) T-cells have been explored as biomarkers in human T1D. However, intra-individual temporal variation of these parameters has not been assessed systematically over time. We determined the va...

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Bibliographic Details
Main Authors: Ghanashyam Sarikonda, Jeremy Pettus, Sowbarnika Sachithanantham, Sonal Phatak, Jacqueline F Miller, Lakshmi Ganesan, Ji Chae, Ronna Mallios, Steve Edelman, Bjoern Peters, Matthias von Herrath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817042?pdf=render

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http://europepmc.org/articles/PMC3817042?pdf=render

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