Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin synthesis was identified in a variety of organs and recently it was shown to be produced in the mitochondria. Since mi...

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Bibliographic Details
Main Authors: Russel J. Reiter, Dun Xian Tan, Sergio Rosales-Corral, Annia Galano, Mei-Jie Jou, Dario Acuna-Castroviejo
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
reactive oxygen species
oxidative stress
molecular pathways
sirtuins
antioxidant enzymes
oxidative phosphorylation
Online Access:http://www.mdpi.com/1422-0067/19/8/2439

Internet

http://www.mdpi.com/1422-0067/19/8/2439

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