Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilage

Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilage

According to the general understanding, the chondrocyte lineage terminates with the elimination of late hypertrophic cells by apoptosis in the growth plate. However, recent cell tracking studies have shown that murine hypertrophic chondrocytes can survive beyond “terminal” differentiation and give r...

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Bibliographic Details
Main Authors: Jung Park, Matthias Gebhardt, Svitlana Golovchenko, Francesc Perez-Branguli, Takako Hattori, Christine Hartmann, Xin Zhou, Benoit deCrombrugghe, Michael Stock, Holm Schneider, Klaus von der Mark
Format: Article
Language:English
Published: The Company of Biologists 2015-07-01
Series:Biology Open
Subjects:
Hypertrophic chondrocyte
Osteoprogenitor cell
Transdifferentiation
Trabecular osteoblast
Online Access:http://bio.biologists.org/content/4/5/608

Internet

http://bio.biologists.org/content/4/5/608

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