STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5

STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5

Summary: Loss of midbrain dopaminergic (mDA) neurons and their axons is central to Parkinson's disease (PD). Growth differentiation factor (GDF)5 is a potential neurotrophic factor for PD therapy. However, the molecular mediators of its neurotrophic action are unknown. Our proteomics analysis s...

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Bibliographic Details
Main Authors: Jayanth Anantha, Susan R. Goulding, Sean L. Wyatt, Ruth M. Concannon, Louise M. Collins, Aideen M. Sullivan, Gerard W. O'Keeffe
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Molecular Biology
Neuroscience
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306490

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http://www.sciencedirect.com/science/article/pii/S2589004220306490

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