Genome-wide DNA methylation analysis on C-reactive protein among Ghanaians suggests molecular links to the emerging risk of cardiovascular diseases

Genome-wide DNA methylation analysis on C-reactive protein among Ghanaians suggests molecular links to the emerging risk of cardiovascular diseases

Abstract Molecular mechanisms at the intersection of inflammation and cardiovascular diseases (CVD) among Africans are still unknown. We performed an epigenome-wide association study to identify loci associated with serum C-reactive protein (marker of inflammation) among Ghanaians and further assess...

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Bibliographic Details
Main Authors: Felix P. Chilunga, Peter Henneman, Andrea Venema, Karlijn A. C. Meeks, Ana Requena-Méndez, Erik Beune, Frank P. Mockenhaupt, Liam Smeeth, Silver Bahendeka, Ina Danquah, Kerstin Klipstein-Grobusch, Adebowale Adeyemo, Marcel M.A.M Mannens, Charles Agyemang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-021-00213-9

Internet

https://doi.org/10.1038/s41525-021-00213-9

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