Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor

Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor

Background: Disruption of bile acid (BA) homeostasis plays a key role in intestinal inflammation. The gut-liver axis is the main site for the regulation of BA synthesis and BA pool size via the combined action of the nuclear Farnesoid X Receptor (FXR) and the enterokine Fibroblast Growth Factor 19 (...

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Bibliographic Details
Main Authors: Raffaella Maria Gadaleta, Oihane Garcia-Irigoyen, Marica Cariello, Natasha Scialpi, Claudia Peres, Stefania Vetrano, Gionatha Fiorino, Silvio Danese, Brian Ko, Jian Luo, Emanuele Porru, Aldo Roda, Carlo Sabbà, Antonio Moschetta
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300943

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http://www.sciencedirect.com/science/article/pii/S2352396420300943

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