A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase

A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase

DNA replication is mediated by a multi-protein complex known as the replisome. With the hexameric MCM (minichromosome maintenance) replicative helicase at its core, the replisome splits the parental DNA strands, forming replication forks (RFs), where it catalyses coupled leading and lagging strand D...

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Bibliographic Details
Main Authors: Benoît Falquet, Ulrich Rass
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-01-01
Series:Microbial Cell
Subjects:
replication stress
DNA repair
genome stability
replication fork restart
anaphase bridges
chromosome non-disjunction
structure-specific nucleases
Online Access:http://microbialcell.com/researcharticles/a-new-role-for-holliday-junction-resolvase-yen1-in-processing-dna-replication-intermediates-exposes-dna2-as-an-accessory-replicative-helicase/

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http://microbialcell.com/researcharticles/a-new-role-for-holliday-junction-resolvase-yen1-in-processing-dna-replication-intermediates-exposes-dna2-as-an-accessory-replicative-helicase/

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