XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells.

XB130, a novel adaptor protein, promotes cell growth by controlling expression of many related genes. MicroRNAs (miRNAs), which are frequently mis-expressed in cancer cells, regulate expression of targeted genes. In this present study, we aimed to explore the oncogenic mechanism of XB130 through miR...

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Bibliographic Details
Main Authors: Hiroki Takeshita, Atsushi Shiozaki, Xiao-Hui Bai, Daisuke Iitaka, Hyunhee Kim, Burton B Yang, Shaf Keshavjee, Mingyao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602428?pdf=render