Integrated transcriptomic and epigenomic analysis of primary human lung epithelial cell differentiation.

Elucidation of the epigenetic basis for cell-type specific gene regulation is key to gaining a full understanding of how the distinct phenotypes of differentiated cells are achieved and maintained. Here we examined how epigenetic changes are integrated with transcriptional activation to determine ce...

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Bibliographic Details
Main Authors: Crystal N Marconett, Beiyun Zhou, Megan E Rieger, Suhaida A Selamat, Mickael Dubourd, Xiaohui Fang, Sean K Lynch, Theresa Ryan Stueve, Kimberly D Siegmund, Benjamin P Berman, Zea Borok, Ite A Laird-Offringa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3688557?pdf=render