Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice.

Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice.

BACKGROUND:Voltage-dependent K(+) channels (Kv) mediate repolarisation of β-cell action potentials, and thereby abrogate insulin secretion. The role of the Kv1.1 K(+) channel in this process is however unclear. We tested for presence of Kv1.1 in different species and tested for a functional role of...

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Bibliographic Details
Main Authors: Zuheng Ma, Catharina Lavebratt, Malin Almgren, Neil Portwood, Lars E Forsberg, Robert Bränström, Erik Berglund, Sture Falkmer, Frank Sundler, Nils Wierup, Anneli Björklund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3071710?pdf=render

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http://europepmc.org/articles/PMC3071710?pdf=render

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