Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.

Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.

At the imprinted Rasgrf1 locus in mouse, a cis-acting sequence controls DNA methylation at a differentially methylated domain (DMD). While characterizing epigenetic marks over the DMD, we observed that DNA and H3K27 trimethylation are mutually exclusive, with DNA and H3K27 methylation limited to the...

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Bibliographic Details
Main Authors: Anders M Lindroth, Yoon Jung Park, Chelsea M McLean, Gregoriy A Dokshin, Jenna M Persson, Herry Herman, Diego Pasini, Xavier Miró, Mary E Donohoe, Jeannie T Lee, Kristian Helin, Paul D Soloway
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2475503?pdf=render

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http://europepmc.org/articles/PMC2475503?pdf=render

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