Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

Given the relevance of beige adipocytes in adult humans, a better understanding of the molecular circuits involved in beige adipocyte biogenesis has provided new insight into human brown adipocyte biology. Genetic mutations in SLC39A13/ZIP13, a member of zinc transporter family, are known to reduce...

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Bibliographic Details
Main Authors: Ayako Fukunaka, Toshiyuki Fukada, Jinhyuk Bhin, Luka Suzuki, Takamasa Tsuzuki, Yuri Takamine, Bum-Ho Bin, Toshinori Yoshihara, Noriko Ichinoseki-Sekine, Hisashi Naito, Takeshi Miyatsuka, Shinzaburo Takamiya, Tsutomu Sasaki, Takeshi Inagaki, Tadahiro Kitamura, Shingo Kajimura, Hirotaka Watada, Yoshio Fujitani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5576661?pdf=render

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http://europepmc.org/articles/PMC5576661?pdf=render

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