Clinical-grade human dental pulp stem cells suppressed the activation of osteoarthritic macrophages and attenuated cartilaginous damage in a rabbit osteoarthritis model

Clinical-grade human dental pulp stem cells suppressed the activation of osteoarthritic macrophages and attenuated cartilaginous damage in a rabbit osteoarthritis model

Abstract Background Although increasing evidence has demonstrated that human dental pulp stem cells (hDPSCs) are efficacious for the clinical treatment of skeletal disorders, the underlying mechanisms remain incompletely understood. Osteoarthritis (OA) is one of the most common degenerative disorder...

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Bibliographic Details
Main Authors: Pei-Lin Li, Yu-Xing Wang, Zhi-Dong Zhao, Zhi-Ling Li, Jia-Wu Liang, Qian Wang, Bo-Feng Yin, Rui-Cong Hao, Meng-Yue Han, Li Ding, Chu-Tse Wu, Heng Zhu
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Human dental pulp stem cells
Osteoarthritic macrophages
Cartilaginous damage
Osteoarthritis
Online Access:https://doi.org/10.1186/s13287-021-02353-2

Internet

https://doi.org/10.1186/s13287-021-02353-2

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