Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS)

Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS)

Rheumatoid arthritis (RA) is a common autoimmune disease. The inflammation in joint tissue and system endanger the human health seriously. Methotrexate have exhibited a satisfactory therapeutic effect in clinical practice. The aim of this research was to establish the pharmacological mechanism of me...

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Bibliographic Details
Main Authors: Zhiqiang Pang, Guoqiang Wang, Nan Ran, Hongqiang Lin, Ziyan Wang, Xuewa Guan, Yuze Yuan, Keyong Fang, Jinping Liu, Fang Wang
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
methotrexate
rheumatoid arthritis
inflammation
metabolomics
lipid metabolism
Online Access:http://www.mdpi.com/1422-0067/19/10/2894

Internet

http://www.mdpi.com/1422-0067/19/10/2894

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