High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure.

Preclinical studies of animals with risk factors, and how those risk factors contribute to the development of cardiovascular disease and cardiac dysfunction, are clearly needed. One such approach is to feed mice a diet rich in fat (i.e. 60%). Here, we determined whether a high fat diet was sufficien...

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Bibliographic Details
Main Authors: Robert E Brainard, Lewis J Watson, Angelica M Demartino, Kenneth R Brittian, Ryan D Readnower, Adjoa Agyemang Boakye, Deqing Zhang, Joseph David Hoetker, Aruni Bhatnagar, Shahid Pervez Baba, Steven P Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867436?pdf=render