Precision Medicine Tools to Guide Therapy and Monitor Response to Treatment in a HER-2+ Gastric Cancer Patient: Case Report

Precision Medicine Tools to Guide Therapy and Monitor Response to Treatment in a HER-2+ Gastric Cancer Patient: Case Report

Trastuzumab, has played a major role in improving treatment outcomes in HER-2 positive gastric cancer. However, once there is disease progression there is a paucity of evidence for second line therapy. Patient-derived xenografts (PDXs) in combination with liquid biopsies can help guide individual th...

Full description

Bibliographic Details
Main Authors: Adriana Aguilar-Mahecha, Sarah Joseph, Luca Cavallone, Marguerite Buchanan, Urszula Krzemien, Gerald Batist, Mark Basik
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
precision medicine
patient derived xenograft
ctDNA
gastric cancer
HER-2+
T-DM1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00698/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00698/full

Similar Items