Comparison of the effects of triamcinolone acetonide or platelet-rich plasma on expression of extracellular matrix-related genes in equine healthy chondrocytes in vitro

Comparison of the effects of triamcinolone acetonide or platelet-rich plasma on expression of extracellular matrix-related genes in equine healthy chondrocytes in vitro

ABSTRACT: In healthy cartilage, chondrocytes maintain an expression of collagens and proteoglycans and are sensitive to growth factors and cytokines that either enhance or reduce type II collagen synthesis. In osteoarthritis, pro-inflammatory cytokines, such as IL-6, induce overexpression of metall...

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Bibliographic Details
Main Authors: Heloisa Einloft Palma, Miguel Gallio, Gabriele Biavaschi da Silva, Camila Cantarelli, Kalyne Bertolin, Patrícia Wolkmer, Julien Wergutz, Luciana Maria Fontanari Krause, Alexandre Krause, Alfredo Quites Antoniazzi, Karin Erica Brass, Flavio Desessards De La Corte
Format: Article
Language:English
Published: Universidade Federal de Santa Maria
Series:Ciência Rural
Subjects:
MMPs
IL-6
aggrecan
cartilage
osteoarthritis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000700601&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000700601&lng=en&tlng=en

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