Non-specific Detection of a Major Western Blotting Band in Human Brain Homogenates by a Multitude of Amyloid Precursor Protein Antibodies

Non-specific Detection of a Major Western Blotting Band in Human Brain Homogenates by a Multitude of Amyloid Precursor Protein Antibodies

The use of human post-mortem brain material is of great value when investigating which pathological mechanisms occur in human brain, and to avoid translational problems which have for example been evident when translating animal research into Alzheimer disease (AD) clinical trials. The amyloid β (Aβ...

Full description

Bibliographic Details
Main Authors: Hazal Haytural, Jolanta L. Lundgren, Tansu B. Köse, Tomàs Jordà-Siquier, Marinela Kalcheva, Mohammed Seed Ahmed, Bengt Winblad, Erik Sundström, Gaël Barthet, Lars O. Tjernberg, Susanne Frykman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
amyloid precursor protein
human brain
western blotting
cross-reactivity
η-secretase
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00273/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00273/full

Similar Items