Default Pathway of var2csa switching and translational repression in Plasmodium falciparum.

Antigenic variation is a subtle process of fundamental importance to the survival of a microbial pathogen. In Plasmodium falciparum malaria, PfEMP1 is the major variable antigen and adhesin expressed at the surface of the infected erythrocyte, which is encoded for by members of a family of 60 var-ge...

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Bibliographic Details
Main Authors: Bobo W Mok, Ulf Ribacke, Niloofar Rasti, Fred Kironde, Qijun Chen, Peter Nilsson, Mats Wahlgren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2292259?pdf=render