Blocking Posttranslational Core Fucosylation Ameliorates Rat Peritoneal Mesothelial Cell Epithelial-Mesenchymal Transition

Blocking Posttranslational Core Fucosylation Ameliorates Rat Peritoneal Mesothelial Cell Epithelial-Mesenchymal Transition

Background: Core fucosylation (CF), catalyzed by α-1,6 fucosyltransferase (Fut8) in mammals, plays an important role in pathological processes through posttranslational modification of key signaling receptor proteins, including transforming growth factor (TGF)-β receptors and platelet-derived growth...

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Bibliographic Details
Main Authors: Long-Kai Li, Nan Wang, Wei-Dong Wang, Xiang-Ning Du, Xin-Yu Wen, Ling-Yu Wang, Yi-Yao Deng, Da-Peng Wang, Hong-Li Lin
Format: Article
Language:English
Published: Wolters Kluwer 2017-01-01
Series:Chinese Medical Journal
Subjects:
α-1
6 Fucosyltransferase; Core Fucosylation; Epithelial–Mesenchymal Transition; Peritoneal Fibrosis
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=18;spage=2147;epage=2155;aulast=Li

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http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=18;spage=2147;epage=2155;aulast=Li

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