Illuminating the dynamics of signal integration in Natural Killer cells

Natural Killer (NK) cell responses are shaped by the integration of signals transduced from multiple activating and inhibitory receptors at their surface. Biochemical and genetic approaches have identified most of the key proteins involved in signal integration but a major challenge remains in under...

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Bibliographic Details
Main Authors: Sophie Victoria Pageon, Dominika eRudnicka, Daniel M Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00308/full