βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

Abstract Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. Methods Surgical specimens from 247 patients were analyzed. Βcat...

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Bibliographic Details
Main Authors: Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Katarina Kalavska, Katarina Rejlekova, Daniela Svetlovska, Dusan Macak, Stanislav Spanik, Karol Kajo, Pavel Babal, Michal Mego, Jozef Mardiak
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
βcatenin
WNTβ pathway
PD-L1
Systemic-immune inflammation
Tumor infiltrating lymphocytes
Online Access:http://link.springer.com/article/10.1186/s12885-018-4929-x

Internet

http://link.springer.com/article/10.1186/s12885-018-4929-x

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