Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors

Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors

Abstract The potential for adoptive cell immunotherapy as a treatment against cancers has been demonstrated by the remarkable response in some patients with hematological malignancies using autologous T cells endowed with chimeric antigen receptors (CARs) specific for CD19. Clinical efficacy of CAR-...

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Bibliographic Details
Main Authors: Erhao Zhang, Jieyi Gu, Hanmei Xu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cancer
Subjects:
Chimeric antigen receptor T cell
Adoptive cell therapy
Solid tumor
Immunosuppressive microenvironment
Cancer immunotherapy
Online Access:http://link.springer.com/article/10.1186/s12943-018-0759-3

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http://link.springer.com/article/10.1186/s12943-018-0759-3

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